High correlation between the i-STAT measurements and conventional methods has been reported ( 7– 12).
#Potassium poc istat manual#
Therefore, manual correction of the conductivity-based measurement for shifted levels of total protein in the patient’s blood caused by hemodilution is no longer necessary ( 6). Furthermore, hematocrit measured during acute hemodilution, as present during CPB, is adjusted for the estimated level of total protein using the so-called CPB-mode of the i-STAT.
#Potassium poc istat portable#
The i-STAT is a portable hand-held blood analyzer that uses different cartridges for simultaneous measurement of a variety of biochemical parameters. These analyses can easily be performed on the i-STAT point-of-care laboratory system (Abbott Point of Care, East Windsor, NJ). Such point-of-care analyzers allow clinicians and nurses to perform the assays, providing real-time laboratory information at the patient’s bedside.ĭuring cardiopulmonary bypass (CPB) for cardiac surgery and on the intensive care unit (ICU) where hemodynamic changes need to be closely monitored, clinicians are particularly interested in blood gases, electrolytes, and hematocrit values. For this reason, point-of-care analyzers are an attractive therapeutic instrument in acute patient care. The availability of faster test results expedites diagnosis and the initiation of treatment. Point-of-care testing has been developed to provide improvement in convenience, patient care, and turn-around time ( 1– 5). However, the discrepancy in hematocrit bias shows that accuracy established in one patient population cannot be automatically extrapolated to other patient populations, thus stressing the need for separate evaluation. The i-STAT analyzer is suitable for point-of-care testing of electrolytes and blood gases in critically ill patients, except for high pO 2. 0001) in the hematocrit range below 25% ( n = 11) using the i-STAT. In contrast to hematocrit measured during CPB, hematocrit using the non-CPB mode in the non-cardiac intensive care population showed an underestimation up to 2.2% ( p <.
In the normal pO 2 range (10.6 < pO 2 <13.3 kPa), the performance of the i-STAT was comparable to the RapidLab. 0001 when 10 < pO 2 <30 kPa) and in the intensive care unit ( r = −0.61, p <. 03) and for pO 2 > 10 kPa during CPB ( r = −0.59, p <. A clear linear trend in deviation of i-STAT from RapidLab was noticed for pH during CPB ( r = 0.32, p =. Point-of-care electrolytes and blood gases had constant deviation, except for pH, pO 2, and hematocrit. The agreement analysis for quantitative data was used to compare i-STAT to RapidLab for blood gas/electrolytes and for hematocrit with the Sysmex instrument.
During a 3-month period, 48 blood samples from patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) and 42 blood samples from non-cardiac patients who needed intensive care treatment were analyzed on both the i-STAT analyzer (CPB and non-CPB mode, respectively) and our laboratory analyzers (RapidLab 865/Sysmex XE-2100 instrument). We therefore evaluated the analytical performance of the i-STAT point-of-care analyzer in two critically ill adult patient populations. This is especially true when biochemical parameters exceed the clinical reference range, in which acute and effective treatment is essential. Point-of-care analyzers may benefit therapeutic decision making by reducing turn-around-time for samples.
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